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KMID : 0861420120160010096
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Korean Journal of Nuclear Medicine Technology
2012 Volume.16 No. 1 p.96 ~ p.101
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A Study on Glomerular Filtration Rate Comparisons between Gates Method and Modified Gates Method used in Dynamic Renal Scintigraphy
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Ham Joon-Chul
Bahn Young-Kag
Park Min-Soo
Cho Seok-Won
Lim Han-Sang
Kim Jae-Sam
Lee Chang-Ho
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Abstract
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Purpose: Glomerular filtration rate is an important index for assessment of renal function, early discovery of renal disease, and progress observation of chronic renal disease patients. In the present study, the objective is to conduct a comparative analysis of differences between Gates and Modified Gates method in dynamic renal scintigraphy based on MDRD (Modification of Diet Renal Disease) formula using blood collection.
Materials and Methods: Renal scintigraphy was performed for 45 patients who visited our hospital between November 2010 and August 2011. For 20 patients of those tested, glomerular filtration rates from Gates method and MDRD
formula using AGUS equipment, were compared. For the other 20 patients, glomerular filtration rates from Modified Gates method and MDRD formula using INFINIA equipment. Finally, Gates and Modified Gates method were compared for 5 patients who indicated no change in glomerular filtration rates from MDRD formula during progress observation.
Results: Glomerular filtration rates from both Gates and Modified Gates method showed a high correlation with those from MDRD formula (p<0.01, r=0.903, r=0.867), with a paired difference mean for Gates method of 2.05 2.54 mL/min/1.73 m, and that for Modified Gates method of 25.2±3.71 mL/min/1.73 m. Finally, the values for Gates method and those for Modified Gates method showed a high correlation for the five patients (p<0.05, r=0.949), with a paired difference mean of 20.4±8.84 mL/min/1.73 m.
Conclusion: Glomerular filtration rates from Gates method, Modified Gates method and MDRD formula showed mutually high correlations. If the tests are performed with recognition for the correlations between Gates and Modified Gates method used in a dynamic renal scintigraphy, then an accurate assessment of renal function is considered possible with an improved diagnostic ability.
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KEYWORD
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Renal scintigraphy, Gates method, Modified Gates method, MDRD (Modification of Diet Renal Disease)
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